Metabolomics, Genomics, and Risk for Alzheimer’s Disease

Tuesday, March 6, 2018 -
4:00pm to 5:00pm
Rm. 1360 Biotechnology Center, 425 Henry Mall

Speaker Name: 

Burcu Darst

Speaker Institution: 

Epidemiology Program, University of Wisconsin-Madison




Although Alzheimer’s disease (AD) is a highly prevalent and heritable disease, little is known about the underlying mechanisms that lead to its onset. Investigating the metabolomics and genomics of risk factors preceding its diagnosis could be an informative approach to better understand this complex disease. In this talk, I will describe longitudinal analyses investigating associations between metabolites and an aspect of cognitive function that declines early in the disease progression. Further, I will also describe an integrative analysis used to identify groups of metabolites and genes that could influence AD risk factors.